Process Flow Controllers
Medchemexpress LLC Ars-853 | 1629268-00-3 | 98.39% | 432.94 | 1 ML
ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. It inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
- Cell-active, selective, covalent KRAS G12C inhibitor.
- IC50 of 2.5 μM for KRAS(G12C).
- Inhibits mutant KRAS-driven signaling.
- Reduces GTP-bound KRAS levels by more than 95% at 10 μM in KRASG12C-mutant lung cancer cells.
- Inhibits proliferation with an IC50 similar to its target inhibition IC50.
- Selectively reduces KRAS-GTP levels and RAS-effector signaling in KRASG12C-mutant cells.
- Induces apoptosis in four KRASG12C mutant cell lines.
Selleck Chemical LLC ARS-1323-E1856-1G
ARS-1323 is the racemic mixture containing ARS-1620 and a potent inhibitor of mutant KRAS G12C It can be used in research for biochemical binding screens as companion imaging drugs (CID) for KRAS G12C
Selleck Chemical LLC ARS-1323-E1856-5MG
ARS-1323 is the racemic mixture containing ARS-1620 and a potent inhibitor of mutant KRAS G12C It can be used in research for biochemical binding screens as companion imaging drugs (CID) for KRAS G12C
Selleck Chemical LLC ARS-1323-E1856-100MG
ARS-1323 is the racemic mixture containing ARS-1620 and a potent inhibitor of mutant KRAS G12C It can be used in research for biochemical binding screens as companion imaging drugs (CID) for KRAS G12C
Bertin Corp Coriolis Compact air sampler Civil security
Coriolis Compact air sampler Civil security including: 1 Coriolis Compact, 1 Coriolis Compact charger, 20 Cones (included air intake), 1 Shoulder strap, Ruggedized Transport box
